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我在《泰晤士报》上读到篇文章 I read this piece in"The Times"
是一个需要换气管的小女孩 about this little girl who needs a new windpipe.
她叫汉娜·沃伦 Name's Hannah Warren.
她家人在跟欧洲一位医生合作 Her family's working with this doctor in Europe.
保罗·马基亚里尼博士 Dr. Paolo Macchiarini.
我的研究方向是通过开发生物合成气管 The focus of my research is tracheal transplants
在干细胞的参与下 with the help of stem cells
进行气管移植 by developing biosynthetic tracheas.
你等于是让身体相信 So you're basically tricking the body
植入物已经是自身的一部分了 into thinking the implant's already a part of you.
你有兴趣做我助手吗 Will you be interested in assisting?
有 当然有 Yes. Yes.
不知道你是否有兴趣合作 I was wondering if you would be interested
用我们的气管在老鼠身上做实验 in collaborating on rat trials to test our tracheas.
-当然 -欢迎加入 - Absolutely. - Welcome to the team.
这是美国首例人工气管 So this is the first artificial- trachea transplant
移植手术 in the U. S.
我想把文章的焦点放在汉娜身上 and I want Hannah's journey to be the focus of the piece.
手术进行得很顺利 Surgery went well.
我已经观察你一段时间了 I have watched you for a while now.
你做的一切堪称奇迹 What you did, it was a miracle.
保罗 我不应该 Paolo, I shouldn't.
似乎没什么科学基础 The science doesn't seem sound.
这与你擅长的科学不同 It's not exactly your kind of science.
我承认我不理解 I will admit I don't get it.
手术刀 Knife.
她在做过气管移植后 活得 After the operation, she's healthy and happy
很开心 很健康 with her donor trachea.
芝加哥 汉娜·沃伦五号病人 术后两个月
汉娜·沃伦将会成为生物合成气管移植 Hannah Warren will be the youngest patient
史上最年轻的病例 ever to receive a biosynthetic tracheal transplant.
好了 这里停一下 Okay, stop right there.
把这里换成马基亚里尼医生 Let's swap this out to play over Dr. Macchiarini talking
第一次诊断后的谈话 about the initial diagnosis.
我觉得还需要加一点父母的镜头 I think we still need a little more B- roll
但节目马上就要定版了 with the parents, but we are close to locking.
-你没事吧 - 对我没事 - You okay? - Yeah, I'm okay.
嗨 Hi.
我正在聊你呢 I was just talking about you.
嗯 贝妮塔 Uh, Benita.
达里尔 Daryl?
我打电话是 I called to, um- -
我打电话是想告诉你 I called to tell you she, uh- -
她走了 she's gone.
什么 What?
汉娜已经不在了 Hannah's gone.
什么叫她不在了 What- - what do you mean she's gone?
出现了并发症 It was- There were complications.
她的肺部 因为经历了太多次治疗 Her- - her lungs, after all the time in the hospital,
她 她的身体无法再 she just- - her body couldn't, um...
汉娜去世了 Hannah's gone.
我们一直跟她待在一起 她的情况不断恶化 We were with her, and she just kept getting worse.
我们以为她能挺过来 We thought maybe she was gonna- -
可是 that it would pass, but, uh- -
妈 你电话响了 Mom, your phone.
-工作上的事吗 -不是工作 - Is it work? - No, it's not work.
你为什么想梳辫子了 孩子 What's up with the braids, kiddo?
你一周从没梳过两次相同的发型 I haven't seen you repeat a hairstyle twice,
更别说一周三次了 let alone three times, in a week.
爸爸喜欢我这么梳 Dad liked my hair this way.
我也很想他 I miss him, too.
但 你看起来真的很棒 But I think you look great.
准备好去上学了吗 You ready for school?
你来这里做什么 What are you doing here?
我想确保你没事 I wanted to make sure that you're okay.
你不接我电话 不回我短信 You're not answering my phone calls, my texts.
你不该来这里 You shouldn't be here.
我知道 你听说了汉娜的事 I know you heard about Hannah.
我只是想确保你没事 贝尼塔 I just wanted to make sure that you're okay, Benita.
你不是告诉我她有好转吗 I thought she was getting better.
-出现了并发症 -并发症 － There were complications. - "Complications.
脆弱的原生组织 ”Fragile native tissue.
让她的肺部越来越虚弱 Weakening of the lungs"
我看过报告了 保罗 我懂医学 I- I read the reports, Paolo. I know the medicine.
可你却告诉我她会好转 But you told me she was getting better.
她病得很重 She was very sick.
她本来就要死了 And she was going to die.
我尽力了 I tried.
你以为我不难过吗 You think that I'm not upset?
但我不会放弃的 But I won't give up.
我没有放弃的权利 I don't have the right to give up.
保罗 别这样 我做不到 No, Paolo, don't. I- I can't do this.
咱们就直接承认了吧 好吗 Let's just call it what it is, okay?
承认什么 What is it?
这是个错误 A mistake.
各位同事 董事会成员 Colleagues, board members,
很高兴大家能出席 we are so glad to have you here
这个重要的时刻 for this momentous occasion.
明天 我们将进行首例生物人造支架 Tomorrow we will perform the first- ever human transplant
的移植手术 using a bioartificial scaffold.
我们的病人叫安德马力亚姆·贝耶恩 Our patient is Andemariam Beyene,
一位生活在冰岛的36岁 a 36- year- old Eritrean PhD student
厄立特里亚博士生 living in Iceland.
两年前 他的气管长出了 Two years ago, he developed a malignant tumor
恶性肿瘤 in his windpipe.
多次放疗和手术干预 They have tried radiation and surgical intervention.
都失败了 AlI failed.
所以他的医生把他介绍给了我们 So his doctors referred him to us.
大家都知道 我们只有在 As you all know, we only have approval
病人病情危急 标准治疗无效时 to perform this procedure as compassionate use,
才会批准这种手术 a last resort.
我们为贝耶恩先生量身定做了 We have designed a biosynthetic trachea
一套生物合成气管 tailor- made to Mr. Beyene's anatomy,
精确到每一微米 down to the last micrometer.
这例手术将使我们学院成为 And this truly is the breakthrough
这种医疗手段的全球目的地 that will launch us as a global destination
这无疑是一种重大突破 for this kind of medicine.
女士们 先生们 Ladies and gentlemen,
请允许我展示再生医学的未来 I present to you the future of regenerative medicine.
几周内 它就会长出人体组织 Within weeks, it will grow tissue,
才成为一个真正的活气管 transforming into an actual, living trachea.
安德马力亚姆·贝耶嗯 2号病人 第一例生物气管移植
马基亚里尼医生 很抱歉 Dr. Macchiarini, I am sorry.
我不想再做手术了 I no longer wish to have the surgery.
我们觉得风险实在太大 We feel it is too risky.
有顾虑是很正常的 贝耶恩先生 It is completely natural to have concerns, Mr. Beyene.
那根气管是塑料的 The trachea, it's plastic.
你怎么能保证 它在我体内会起作用 How can you be sure it will work inside my body?
你这里误会了 There you misunderstand.
它不是塑料的 It is not plastic.
气管是医用级的 The trachea is medical- grade
高分子纳米复合材料制成 polymeric nano- composite material.
-我可以进来吗 -当然 - If I may. - Yeah, of course.
贝耶恩先生 你在冰岛研究熔岩洞 Mr. Beyene, you're studying lava tubes in Iceland.
-对吗 -对 - Is that right? - Yes.
我认为细胞再生过程 I believe the recellularization process
也是这个道理 is just like that.
当火山爆发时 When a volcano erupts,
地下的熔岩河形成了管洞 underground lava rivers create tubes.
熔岩干涸后 这些管洞留了下来 When the lava drains, the tubes remain,
但它们变得坚如磐石 but now they're rock solid.
成为了地球的一部分 They become a part of the Earth.
也就意味着持久永恒 And that means they last forever.
你的干细胞对 That's what your stem cells will do
合成气管也是这个作用 to the synthetic trachea
让它永远成为你的一部分 to make it last forever as a part of you.
你要让我丈夫做第一例受试者 You're asking my husband to be the first
却不保证手术一定有效 but offer no guarantee the procedure will work.
是 我们保证不了 No, we cannot offer guarantees
滥做保证是不负责任的 because it would be irresponsible to do so.
医学上不存在绝对可靠一说 Nothing is guaranteed in medicine.
就在一年前 Even just a year ago,
你的选择还很有限 your options would have been much more limited.
现在 你很幸运能成为第一个 You are very lucky to be the first.
你的医生让你来找我们 Your doctors referred you to us
因为其他治疗方案统统失败 because the other treatments failed you.
你的预期寿命只剩六个月了 You could have as little as six months to live.
你要是想看着儿子长大 这就是最好的机会 This is your best chance to see your son grow up.
好吧 Okay.
不投入个人感情是很难的 I think it's very difficult to keep an emotional distance,
尤其这个病人还是个孩子 especially if it is a child.
你还撑得住吗 How you holding up?
真希望自己能麻木一点 I wish I felt numb.
我现在心里 I just feel
五味杂陈 everything.
你休息一下吧 B Give yourself a break, B.
别那么着急走出来 You're not on a schedule here.
一定要难受过才会好 It's gonna take what it takes.
你知道吗 汉娜·沃伦和约翰 You know, with Hannah Warren and John...
死的人也太多了 it's just a whole lot of death.
丽兹怎么样了 How's Lizzi?
她蛮安静的 She's really quiet.
她应该是想在我面前装作无事 I think she's pretending to be okay for me,
这反而让我更内疚 更难受了 which makes me feel guilty, which makes me feel worse.
她跟她爸的关系真的很好 She's just such a daddy's girl.
真的让我很心碎 And that breaks my heart.
至少你还有心可以碎 At least you still have a heart to break.
是啊 痛苦让我们向死而生 Yeah, the pain reminds us we're alive.
这还不错 It's awesome.
-工作好吗 -还好 - Work is good? - Work is good.
工作还好 Work is good.
那篇报道进展如何了 Hey, how's that piece coming along?
没进展了呢 Hey, it's not.
因为 It's.
这是一篇报道未来医学的特别节目 a special about the future of medicine.
本应该给人希望 It's supposed to be hopeful.
可我现在没故事可写了 And now I don't have a story at all.
-那他呢 -他怎么了 - What about him? - What about him?
把焦点转移到他身上 Shift the focus to him, you know?
马基亚里尼医生 创造奇迹的人 "Dr. Macchiarini, Miracle Man"- -
代际医学的先驱 a look at the pioneer of generational medicine.
-再生医学 -没错 Regenerative. - Exactly.
那汉娜怎么办 But then what about Hannah?
你仍可以把她安排进主叙事中 She'd still be part of the main story.
医学上的突破总是伴随着挫折 Medical breakthroughs are always paved with setbacks.
不代表马基亚里尼的研究 It doesn't mean that Macchiarini's work
就不值得相信 isn't worth believing in.
聚焦在点燃大家希望上 Hold on to the hopeful.
这可是你的专长 If anybody can make it happen, it's you.
从什么时候开始疼的 When did the pain start?
过去几周都断断续续的 Um, off and on for the last few weeks.
我以为是压力太大 I just thought it was stress or something.
是刺痛 钝痛还是灼痛 Would you describe the pain as sharp, dull, or burning?
刺痛 就像啊 Sharp, like- Aah!
就像被人捅了一样 噢 Like someone's stabbing me. Ow.
需要做全血细胞计数 肝酶 Let's get a CBC, liver enzymes,
尿检 腹部和骨盆的CT urine test, and a CT of the abdomen and pelvis,
外加30毫克的妥拉多止痛 plus 30 milligrams of Toradol for the pain.
－ 所以是阑尾炎么 不是阑尾炎 So it's my appendix? - It's not your appendix.
什么 不不不 What? No, no, no, no, no.
我有一个女儿她才九岁 I have a daughter. She's nine years old.
她刚失去了父亲 She just lost her father.
我绝对不能倒下 I can't have something wrong with me.
我们只想做些检查 确认下情况 We just need to run some tests to see what's going on.
医生 他们在等你呢 Doctor, they're waiting.
你要给谁打电话吗 Is there anyone you want to call?
你好打扰一下 Hi, excuse me.
－ 嗨嗨 - Hi. - Hi.
谢谢你能过来 我很抱歉 Thank you for coming. I'm sorry.
没事 接到你电话我很开心 No, no, I'm glad you called.
－现在还痛吗还痛 - Has the pain subsided? - No.
而且我觉得更疼了 I think it's worse, actually.
－ 医生怎么说啥都没说 - What did the doctor say? - Nothing.
就做了一堆测试也没人通知情况 They just ran a bunch of tests, and no one's told me anything.
把我一个人晾在这儿 I've just been sitting here by myself.
CT扫描显示你有子宫肌瘤 You CT scan shows uterine fibroids.
什么那是什么癌症吗 What? What is that? Is that cancer?
完全不是 这很常见 Not at all. They're very common.
介意我看一下吗好的 - Is it okay if I take a look? - Yeah.
－ 行吧行 - Yeah? - Okay.
－ 可能会有点疼没事 - This might hurt a little bit. - Okay. All right.
好吧 Okay.
我能摸到到两个 Yeah, I can feel two.
应该跟葡萄柚差不多大 They're about the size of grapefruits.
什么 What?
没有听上去那么糟糕 It sounds much worse than what it is.
别担心 他们会帮你割掉的 Don't worry. They will have them removed.
所以我必须得手术么 So I have to have surgery?
对但这手术很常见 Yeah, but it's a very common procedure.
医生一定会把细节交代到的 I'm sure your doctor will walk you through everything.
你会没事的 You're gonna be fine.
相信我 Trust me.
2012 斯德哥尔摩
他一上来就让你加班啊 He's got you working late already?
我在做准备 I'm preparing.
这是医生的工作 It's something doctors do.
-你也该试试的 -了解 - You should try it. - Noted.
等文章发表了我睡觉的时间还多呢 I'll sleep when I'm published.
你为什么不喜欢他 Why don't you like him?
我谁都不喜欢 I don't really like anybody.
这倒不假 That's true.
可是呢 咽喉手术在外科医生中并不受欢迎 Still, so few surgeons want to operate on the throat at all,
而他却引入了干细胞再生 and he throws in stem- cell regeneration.
你对他的研究不感兴趣吗 Aren't you interested in his work?
是呢 是呢 我觉得这一切 Yes, yes, I find it all very
都非常有趣 interesting.
你个混蛋 You're an ass.
你来看看这个 Look at this.
他必须识别气管周围的手术平面 He has to identify the surgical planes bordering the trachea,
避免肿瘤扩散 avoid tumor dissemination,
同时不暴露出喉头 all without exposing the larynx,
甲状腺 食道 the thyroid, the esophagus.
你有发表意见的权利 Say what you want.
但马基亚里尼医生确实很有种 Dr. Macchiarini's got some balls.
这就是成功所需的吧 有种 I guess that's what it takes, huh- - some nice big balls?
抱歉 我不是要有意冒犯你 Sorry, I didn't mean to offend you.
是呢 你就是想说我没种 Yes, I have tiny balls.
一位优秀外科医生 知道什么时候不该动刀 You know, a good surgeon knows when not to cut.
得了吧 我受够了总是畏畏缩缩 Fuck that. I'm tired of being on the verge of something.
过于谨慎而切不干净 这项研究极具开创性 Too afraid to make the cut- - this is groundbreaking work.
我一定要参予 I'm getting in.
你小小心点就行 Just watch your back.
我总是很小心 I always do.
斯文森医生 Dr. Svensson.
马基亚里尼医生 Dr. Macchiarini? Uh.
试验似乎进行得很顺利 Oh, the trials seem to be proceeding nicely.
是啊 Uh, yes.
一切正按计划进行 Um, we're on schedule.
很好 Good.
目前有什么好消息吗 Any exciting conclusions so far?
目前 你知道 还没有 Well, nothing- - you know, nothing
还没有切实的成果 really determinable yet.
当然 我现在还 Of course, I won't be able to truly discern
还什么都看不出来 要等到 any results until- -
对 等到你完成试验才行 Yeah, until you completed the trials, of course.
你应该能想象得到 我对于试验结果 - As you can imagine, I'm- - - I'm very anxious
十分期待 to see any results- - positive or otherwise.
就是那些植入了人造气管的 Well, on the test rats
试验老鼠 that have received synthetic tracheas,
目前为止 还没有发现负面反应 so far none have responded negatively.
那 那太好了 Well, that- - that is excellent.
但你也知道 我们还在收集数据 But as you said, we're still gathering data.
这个试验的目的 the purpose of this trial
就是为了观察客观结果 is to witness objective results, of course.
当然 这是当然 Of course, of course.
请问是有什么因素引起了 May I ask, is there anything in particular
-你的关注吗 -没 完全不是 - that is concerning you? - Oh, no, not at all.
我百分之百相信你的专业 医生 I have complete faith in your research, Doctor,
还有我的专业 as well as my own.
那就先不打扰了 I'll just leave you to your work.
好吧 Okay.
是的 Yeah.
-谢谢 -没问题 Thank you. - Yeah, no problem.
哦 谢谢 太谢谢了 Oh, thank you, thank you, thank you.
天呐 快扶我起来 Oh, my God, please.
真希望我对你也能有这种影响 Wow, I wish I had that effect on you.
48小时断绝咖啡因 48 hours without caffeine?
我名字今天被写啥了 Who am I today?
我帮他们拼好了你的名字 I spelled your name for them.
-感觉好点没 -嗯嗯 You're feeling better? - Mm- hmm.
感觉像轻了两个葡萄柚 I am. Like two grapefruits lighter.
谢谢你 真的 Thank you, really.
我的荣幸 Pleasure.
保罗 Paolo...
过去几个月我们都失去了很多 we've both been through a lot of loss the past few months.
我知道自己不会死在里面 可是 And I know I wasn't dying in there, but I- -
我还是很害怕 I was really scared, and it...
就 It just- -
这次事件为我打开了新视角 it put things in perspective for me.
我们在一起 可能会害我丢了工作 名誉扫地 Us together, it could cost me my job, my reputation,
但我认为 为了我们的感情 值得冒这个险 but I think this thing we have, it's worth the risk.
我也如此 For me, too.
有人批评您 You've heard the criticism- -
在拿这些病人冒险 that you're really taking a chance with these patients.
对此 你怎么看 What do you say to that?
我从小受到的教育告诉我 I was raised to believe that if you...
哪怕只有一线机会 也要抓住 if have even one chance, you need to take it,
因为 要么我们放任病人死去 because either that patient will die,
要么我们可以做些新尝试 or we try to do something, even if it's new.
作为一名医生 或是作为一个人 As a doctor and- - and as a human being, I
我扪心自问过 我们有权说不吗 I ask myself, are we allowed to say no?
我觉得没有 I don't think we are.
不久之后 当你接到 And when you got that call later
她去世的电话时 － that- - that she had passed...- Mm.
这对你的打击一定是毁灭性的 It had to be devastating for you.
我一直在想 I couldn't stop thinking...
那个决定真的正确吗 did I make the right decision?
我拼尽全力去救她了吗 Did I do everything to save her?
世界上有这么多病人 There are so many patients all around the world
都需要这个手术 who need this procedure.
我们应该为所有这些人 We should really try to achieve this
做到这一点 for all of them,
因为即便要直面失败 because even in the face of failure,
我们都该心存希望 we should keep hope alive.
大家今天干的不错 Great job today, guys.
马基亚里尼医生 你能稍留几分钟 Dr. Macchiarini, do you mind staying behind
看一下录制安排吗 for a few minutes to go over the schedule?
晚安 各位 Good night.
当然可以 Of course.
所以 So?
所以 So...
我还有一些后续问题要问你 Well, I have some follow- up questions for you
这就是未来 时间大概在 that are gonna happen...
-是吗 -把门关上好吗 - Really? - Behind closed doors, yeah.
很抱歉你要经历这些 I'm so sorry you had to go through this.
没关系的 It's okay.
就是留道疤而已 It's just gonna be a scar.
总有一天 我们会生活在一个 One day we will live in a world
不需要开刀就能治病的世界 where we won't have to cut people open to fix them.
你会看到的 You'll see.
你曾有过疑虑吗 Do you ever have any doubts?
当然有过 Of course I do.
真的吗 Really? - Mm- hmm.
因为你似乎总是信心满满 Cause you seem so sure of all of it.
哪怕是那些担心的事 Even the things that could go wrong,
最后都成了真 that have gone wrong.
你依然勇往直前 you just keep moving forward.
我常常会想起那些前辈们 I think a lot about the ones who came before me.
比如托马斯·斯塔兹 Like Thomas Starzl- -
他开创了第一例肝移植手术 he started the first liver transplants.
他的第一批病人都死了 - His first patients died. - Hmm.
或是克里斯蒂安·巴纳德 Or Christiaan Barnard.
他做了第一例心脏移植手术 he performed the first heart transplant.
大家对他口诛笔伐 People threw rocks at him.
所有人都觉得他疯了 Everybody thought he was crazy.
我相信大家看他的眼神 I'm sure people looked at him the same way
就跟你现在看我一样 that you're looking at me right now.
汉娜死后 我确实失去过信心 When Hannah died, I did lose faith.
但是以上那些医生 But these doctors, they- -
他们也坚信过 努力过 坚持过 they believed, they worked, they persevered
直到拼出了一条路 until they found their way.
作为第一个吃螃蟹的人 Being the one to try something new,
你需要把个人得失放在一边 no matter the personal cost,
关键是要推动医学进步 is vital to move medicine forward.
这至关重要 It's vital.
我相信我们所做的事 And I believe that the work that we're doing
会拯救很多生命 is going to save many lives.
我也这么相信 I believe it will, too.
嗨 亲爱的 我在巴塞罗那想念你 Hi, my love. I'm here, missing you in Barcelona.
柠檬树已经在等着你了 The lemon trees are ready for you.
我等不及要去吃寿司卷了 Oh, there is a sushi roll with my name on it.
-贝妮塔 -哦 对 一起午餐 - Benita? - Hmm? Oh, yeah, lunch.
-准备好了吗 -抱歉 - You ready? - Sorry. Yeah.
很好 Good.
-嗯 -过来 来嘛 - Mm. Come on, come on
不 我理解 这些信息很棒 No, I hear you. The information is great.
但我需要另一个消息源 But I'm going to need another source on it
才能证实她的说法 to confirm her account.
好的 你能发邮件给我吗 Sure. Could you email that to me?
听起来不错 Wow, that sounds good.
是的 Yeah.
-是丽兹打来的 好的 -我会想你的 - It's Lizzi. Okay. - I'll miss you.
你说 请讲 Yeah. Sure.
我没意见 It's okay with me.
只要奥布里妈妈同意 你就可以在她家留宿 If it's okay with Aubrey's mom, you can sleep over.
对 我也爱你 拜拜 Okay. I love you, too. Bye.
-你刚是说“留宿”吗 -对 － Did you say"sleep over"? - Yeah.
要不我改签下航班 Maybe I could change my flight.
还能这样操作啊 Oh, I didn't know that was an option.
嗯哼 Mm- hmm.
-什么 -滚石乐队更性感 What? - The Stones are sexier.
-不不不 -讨论结束 - No, no, no. - That's it.
这俩根本就没有可比性 How can you even compare them?
我从来都这么认为 也不会为此道歉 I've always thought this, and I'm not going to apologize.
《黑鸟》 "Blackbird, "um...
《亲爱的玛莎》 "Martha My Dear, "
《在我吉他温柔哭泣时》《洛基浣熊》 "While My Guitar Gently Weeps, ""Rocky Raccoon. "
怎么 现在是要列歌单了吗 Okay, now we're listing songs?
-是的 -《满足》 Yeah. - "Satisfaction"...
《给我栖身之所》 Oh. - "Gimme Shelter, "
-《同情魔鬼》 -不行 "Sympathy for the Devil. "- No.
这个问题没的讨论 No, we can't have this conversation.
太可怕了 我不得不跟你分手了 This is terrible. Now I have to leave you.
-你要离开我吗 -我会离开你的 - Are you gonna leave me? - I'm gonna leave you.
你要为了披头士离开我 Are you gonna leave me for The Beatles?
-这个问题非常严肃 -他们都快 This is a very, very...- They're almost- -
-他们都快死绝了 -云泥之别 AlI of them are dead, almost. - Important distinction.
意大利版《时尚》别出心裁嘛 Italian"Vogue, "nice touch.
给丽兹的 For Lizzi. - Ah.
嘿 丽兹 我朋友保罗来了 Hey, Lizzi? My friend Paolo is here.
-你朋友 -我朋友 - Your"friend"? - My friend.
Cacio的意思是“奶酪” "Cacio"means"cheese, "
pepe的意思是“胡椒” and "pepe"means"pepper. "
所以 这就像意大利的通心粉和奶酪 So it's like Italian mac and cheese.
胡椒 你知道的 pepe And pepper, you know, "pepe. "
好好吃啊 对不对 It's delicious, right?
你觉得呢 孩子 What do you think, kiddo?
我不喜欢 I don't like it.
你妈妈说 你会拉小提琴 Your mom tells me that you play the violin.
-没错 -是吗 - She does, yeah. - Yeah?
她每天都练习 She practices every day.
有时我都不用催着她练 Sometimes I don't even have to ask her to practice.
哇哦 好自觉 Oh, wow. That's impressive.
我都被震惊了 It's impressive,
因为我在你这么大的时 在学钢琴 cause I used to play the piano when I was your age,
但我讨厌练琴 but I hated to practice.
也许咱俩可以合奏一段 Well, maybe we can play together.
你拉小提琴 我弹钢琴 You- - you play the violin, and I play the piano.
为你妈妈办一场音乐会 We make a concert for your mom.
你知道约翰·塞巴斯蒂安·巴赫把小提琴弄掉后 Did you hear what happened when Johann Sebastian Bach
会怎样吗 dropped his violin?
成了巴洛克（坏了） It Baroque.
巴洛克 It Ba- roque.
巴洛克 挺搞笑的 Ba- roque, that's funny.
-我能回房间了吗 -丽兹 拜托 Can I go to my room? - Lizzi, come on, please.
不 没事的 No, it's okay.
不过 丽兹 But, Lizzi
我知道你心里一定五味杂陈 I know that you're feeling a thousand things right now,
很多滋味涌上心头 all at once.
我愿意等你弄清楚对我是什么感觉 And I'm ready to wait for as long as it takes
你需要多久 我就等多久 for you to figure out how you feel about me.
但我跟你做个约定 But I'll make you a deal.
如果你肯了解下 If you let me show you
我有多在乎你妈妈 how much I care about your mom,
我保证永远不会逼你吃我做的 I promise you I will never make you eat
奶酪胡椒面 my cacio e pepe again.
同意吗 Accordo?
同意 Accordo.
晚安 Good night.
她会想明白的 She'll get there.
这需要时间 It takes time.
你做的很好吃 It's really good.
但你听懂那个笑话了吧 巴洛克 But you got it, right, Baroque?
-当然听懂了 -那就好 - I got Baroque. - Okay.
这笑话真可爱 Yeah, it's a cute joke.
再看三页 就熄灯睡觉 好吗 Hey, three more pages, then jammies and lights out, okay?
好的 Okay.
-我爱你 -我也爱你 - I love you. I love you, too.
晚安 Good night.
嘿 妈妈 Hey, Mom?
我喜欢他的口音 I like his accent.
你把碗洗了 开什么玩笑 你都做饭了 What? Are you kidding me? You cooked.
真是的 Get out of here.
怎么啦 What?
有个坏消息 I have bad news.
-我们的巴塞罗那之旅 -不会吧 Our trip to Barcelona- - - No!
-我得取消了 -哦 - I have to cancel. - Oh.
我要去莫斯科 Uh, there's- - there's a new patient
见个新病人 I need to meet in Moscow.
我期待了很久 想看看你的家 I was so looking forward to finally seeing your place.
我知道 亲爱的 很抱歉 I know, my love, and I'm so sorry,
但要是她同意手术 but if she agrees to surgery,
整个实验室就不缺资金了 this could launch funding for the entire lab.
对 我懂 我理解 No, I- I get it, I get it.
我只是 Ijust, um
我要想想 该怎么跟金和其他人交代 have to figure out what to tell Kim and everybody else,
因为我已经请好了假 cause I already took time off.
劳拉还要来跟丽兹一起住 还有 And I have Laura coming to stay with Lizzi and- -
不如你跟我一起去吧 Why don't you come with me?
-去俄罗斯 -去莫斯科 - To Russia? - To Moscow.
我可以带你去莫斯科转转 I can show you off in Moscow.
我不知道诶 I don't know.
别这样 贝尼塔 我想和你在一起 Oh, come on, Benita, I want to spend time with you
不用避忌他人目光 求你了 without having to hide- - please.
在节目播出之前 We have to wait until the special airs
我们还不能公开关系 before we tell anybody anything.
反正俄罗斯又没人认识你 I'm sure our secret will be safe in Russia.
跟我一起来嘛 Please come with me.
-跟我一起来 -好的 Please, come with me. - Okay.
我是说 I mean, who- -
我何德何能 敢对伟大的马基亚里尼医生说不呢 who am I to say no to the great Dr. Macchiarini.
进入病人环状环 Accessing the cricoid ring.
观测到严重感染 很可能是 I see severe infection, most likely caused
对病人过度的放疗引起的 by the excessive radiation treatments on the patient.
软骨坏死 The cartilage is necrotic.
即便他没有死于肿瘤 If the tumor hadn't killed him,
感染迟早也会 it would have been only a matter of time
要了他的命 before he succumbed to infection.
手术刀 Knife.
开始切除 Starting resection.
生物合成气管与切除区域 The biosynthetic trachea will fit perfectly
会完美吻合的 in the resected area.
梅氏剪 Metzenbaum.
好的 Okay.
好 切换氧气输入 Okay, switch the oxygen input.
生理盐水 Saline.
如果气管有泄漏 生理盐水就会出现气泡 Any leaks in the trachea will produce bubbles in the saline.
血氧饱和度呢 Pulse ox?
保持稳定 Holding steady.
没有泄漏的迹象 No signs of leaking.
血氧量98% Oxygen holding, 98%.
见效了 It's working.
恭喜你 医生 Congratulations, Doctor.
好了 给他缝合吧 Okay, let's close him up.
医生 Doctor?
血压下降 BP's dropping.
-他在失血 -生命衰竭 - He's bleeding. - Vitals are weakening.
不可能啊 植入物已经成功了 No, it can't be. The implant is working.
这些血是从哪里来的 Where is this blood coming from?
医生 Doctor?
左颈动脉很可能破裂 The left carotid's most likely ruptured.
我没碰它 甚至都没靠近那个区域 No, I didn't touch it. I wasn't even near it.
你说有他有辐射损伤 You said there was radiation damage.
血氧下降 Losing OX.
也许伤及了血管壁 It must have weakened the vascular wall.
-医生 -血压还在下降 Doctor. - Blood pressure is dropping.
医生 我们得做点什么 Doctor, we need to do something.
-医生 -血氧下降 - Doctor? - Losing oxygen.
医生 Doctor?
保罗 Paolo!
我能搞定 I can fix this.
得赶快稳定他的情况 He needs to be stabilized.
-抽吸 -血压在下降 - Suction? - Blood pressure is dropping.
-找到了 -灼烧 Found it. Cautery.
血压回升 BP is on the rise.
他稳定住了 He's stable.
让马基亚里尼医生缝合 Sutures for Dr. Macchiarini.
你来缝合吧 You should close him.
好了 亲爱的 这边走 AII right, my love, this way.
我刚在跟丽兹发短信 I was texting with Lizzi
在研究怎么拨打网络电话 about setting up our Skype call.
她特别要求你来操作 And she specifically asked for you to jump on.
-是吗 -是的 - Oh, she did? - Yeah.
你用魅力俘获了她 你个大骗子 You charmed her, you big charmer.
打扰下 Pardon me.
是吧台那位先生送的 Uh, compliments of the gentleman at the bar.
谢谢你 Thank you.
敬你 敬我 敬这桶香槟 To you, to me, and to ice buckets, always.
干杯 Cheers.
所以 我们今晚的赞助人是谁 So who is our benefactor this evening?
-我不能透露 -拜托 保罗 - I shouldn't say. - Paolo, come on.
我的工作就是保护线人 I protect sources for a living.
他是个俄罗斯寡头 人脉很广的 He's a Russian oligarch, very connected.
不 别乱看 No, don't look.
有一个由名人 神职人员和总统组成的 There is a network of high- profile patients,
高保密患者人际网 celebrities, clergy, presidents
他们接受秘密治疗 我给他们进行秘密治疗 that are treated in secret, that I treat in secret.
因为他们的身份 Because of who they are,
我必须对我们之间的治疗保密 I have to keep our arrangement quiet.
总统 你是说美国总统吗 Presidents, like U. S. presidents?
保罗·马基亚里尼 明星外科医生 Paolo Macchiarini, surgeon to the stars?
好吧 Okay.
我 反正这种事总要有人做 对吧 I- - Somebody's got to do it, right?
嘘 他们来了 － Shh, they're coming. - Oh.
尤利娅 这是贝妮塔·亚历山大 Yulia, this is Benita Alexander.
-保罗 很高兴见到你 -很高兴见到你 Paolo, good to see you. - It's nice to meet you.
如果你想给我留下深刻印象 医生 If you're trying to impress me, Doctor,
这已经起作用了 it's- - it's working.
尤利娅亲 你值得最好的 Yulia, my dear, for you, only the best.
保罗跟我说你是个舞蹈家 Uh, Paolo tells me you're a dancer.
俄罗斯最棒的 The best in Russia.
在我加入莫斯科大剧院后不久 就遇到了安德烈 I met Andrej not long after I joined the Bolshoi.
我见过她表演《天鹅湖》 I saw her perform in"Swan Lake. "
简直太出色了 She was magnificent.
我只是芭蕾舞团的一员 又不是独舞 I was only part of the corps de ballet, not the soloist.
可我还是深深被她所吸引 Still, I could not take my eyes off of her.
几年前我去伦敦巡演时 While I was on tour in London a few years ago,
遭遇了一场可怕的车祸 I was involved in a horrible car accident.
她能活下来就是个奇迹 It's a miracle she's even alive.
我的气管破裂 我的 My windpipe was broken. My...
一切都分崩离析 Everything was broken.
让我的脖子上留下了一个洞 And it left me with this hole in my neck.
真抱歉 I'm so sorry.
过去是个灯塔而不是港口 The past is a lighthouse, not a port.
我认识了马基亚里尼医生 I found Dr. Macchiarini.
到目前为止 我们只给 Up until now, we have implanted
情况危急的患者做过植入 only patients for compassionate use,
那些如果不植入就会死的患者 those who otherwise would die.
但你让我看到生活的质量 But you have shown me that quality of life
与生活本身一样重要 is nearly as important as life itself.
所以这个手术可做可不做 So this is an elective surgery?
是的 - Yeah. - Mm.
我内心的一部分 A part of me
希望手术后我能重新跳舞 但更重要的是 hopes it will allow me to dance again, but, mostly...
我有个两岁的儿子 萨沙 we have a two- year- old son, Sasha.
我想陪他玩 I want to play with him...
给他唱摇篮曲 Sing him a lullaby.
你是个完美的候选人 And you're the perfect candidate.
年轻 健康 You're young, healthy,
没有其它会导致情况复杂化的疾病 no other medical issues that would complicate matters.
你 你准备好了 You- - you're ready.
我真的不想去瑞典 Mm. I really don't want to go to Sweden.
我希望你能在俄罗斯帮我做手术 I wish you were set up to operate in Russia.
那我正好有好消息给你 Then I have great news for you.
我们的同事 拉斯布里医生 这会儿正在克拉斯诺达尔 Our colleague, Dr. Lasbrey, is setting up facilities
搭建手术设备设施 in Krasnodar as we speak.
你的手术将成为我们在俄罗斯的首例尤利娅 Your procedure will launch our work here in Russia, Yulia.
你可以在这里做手术了 You will have your operation here.
敬保罗·马基亚里尼 - To Dr. Paolo Macchiarini...- Ah.
我们的摇滚明星外科医生 Our rock- star surgeon.
你还好吧 - You okay? - Mm- hmm.
我没事 - Yeah? - Yeah, I'm okay.
这个舞第一次搬上舞台是在1871年 This ballet was first performed in 1871.
你知道 You know- -
你没事吧 Are you okay?
嘿嘿嘿 亲爱的 Hey. Hey, hey, hey, my love.
嘿 你没事吧 Hey, are you okay?
抱歉 我觉得我好像不能 I'm sorry. I don't think I can- -
不不不 我们回家去 不 我们这就走 我再联系你 No, no, no, we'll go home. No, we'll go. I text you.
她会 我再联系你 好吗 No, she's- I'll text you, okay?
-我们走吧 -你确定吗 我是不是 Let's go. - Are you sure? Should I- -
确定 确定 Yes. Yeah, yeah.
你的情况好像越来越糟了 You're getting worse.
你应该让我送你去医院的 You should have let me take you to the hospital.
不 我只想躺下歇会 No, I just want to lie down.
-你好像发烧了 -我有点恶心 - You're burning up. - Mm. I feel sick.
让我帮你检查一下 Let me check something.
手术部位出现了感染 The surgical site is infected.
什么 不可能吧 都是几个月前的事了 What? There's no way. That was months ago.
-现在早该好了啊 -没有 - It's got to be healed by now. - No, it's not.
那要怎么办 要用抗生素还是怎么的 So- - so what, antibiotics or something?
不 现在用抗生素太晚了 No, it's too late for that.
你得了败血症 我需要给你的伤口进行清创 You're in sepsis. I need to debride your wound.
否则你会出现休克的 Otherwise, you will go into shock.
清创是什么意思 "Debride"? What does that mean?
你不会有事的 You're gonna be okay.
你相信我吗 Do you trust me?
移植两个月后 "Two months after transplantation,
患者症状消失 "the patient is asymptomatic,
呼吸正常 无肿瘤 "breathes normally, and is tumor free.
这些结果证明了 "These results are evidence
器官再生的方案 "that a successful organ- regeneration strategy
成功实现 has been accomplished. "
手术的成功 "And the procedure's success provides proof
证明了这种方法的可行性 of the viability of this approach. "
敬马基亚里尼医生 勇于尝试并实现了成功 To Dr. Macchiarini, who dared to make the cut.
干杯 Cheers.
敬安德马力亚姆·贝耶内 To Andemariam Beyene,
勇于为科学献身 who bravely risked his life for science.
干杯 Cheers.
最后 还要敬 And last but not least,
这个大名鼎鼎的《柳叶刀》 to The motherfucking"Lancet"
终于肯发表我们的研究文章 for publishing our research article.
-干杯 -干杯 安德斯 Cheers! - Skol, Anders.
干杯 南森 Nathan, tack.
在《柳叶刀》发表了文章 So published in "The Lancet"- -
基本上就离诺贝尔不远了 you're halfway to a Nobel.
太难喝了 This is shit.
还以为他们会选择品质更好的起泡酒呢 You'd think they would have sprung for better bubbly.
那就去偷别人的喝吧 Then feel free to steal someone else's.
-真不错 -干杯 Fantastic. - Cheers.
没想到会在这见到你 I'm surprised to see you here,
因为我知道你对马基亚里尼的观感 knowing how you feel about Dr. Macchiarini.
有免费香槟啊 Well, free champagne is free champagne- -
-虽然不知道这是不是香槟吧 -当然 or whatever this is. - Of course.
你们一定欣喜若狂吧 You must all be on cloud nine.
我当然很激动 I'm excited, of course,
尽管我还有种感觉 though I also have the feeling of- -
应该怎么说 冒名顶替综合征的感觉 What do you call it? Impostor's syndrome.
为什么 Why?
你在负责马基亚里尼的老鼠试验 You're running Macchiarini's rat trials.
但现在还在试验阶段 Which are still in progress.
马基亚里尼在标题下署了我的名 Macchiarini included my name in the byline,
但我还没提交试验结果呢 but I have yet to submit my results.
欢迎来到科学出版的世界 Welcome to the world of scientific publishing.
我记得有人曾经说过 As I recall someone once saying,
竞争推动进步 "Competition fuels progress. "
-好吧 -我们到了 Okay. - Here we go.
2013纽约 小心椅子 Watch out for the chair.
行吧 但我什么都看不到啊 Yeah, but I can't watch anything.
好了 Okay.
-好了 你可以睁开眼睛了 -不是吧 － Okay, you can open your eyes. - No.
你说过自己想重新弹琴的 You said you wanted to start playing again.
我们可以来个二重奏 - We can do a duet. - Wow.
对 二重奏 Yeah, we can do a duet.
真是太不可思议了 谢谢 This is incredible. Thank you.
小心你的伤口 - Careful with your stitches. - Aw.
过来 宝儿 Love, come here.
太感谢了 太酷了 Thank you so much. Wow, this is so cool.
但首先 我得记起怎么弹才行 But first, I have to remember how to play.
-我去拿手机 -太酷了 － Oh, let me get my phone. - This is so cool.
谢谢 Thank you.
知道我会想念 ♪Knowing I'll be missing ♪
故乡的圣诞前夜 ♪Christmas Eve in my hometown ♪
谢谢 - Thank you. - Mm.
你还好吗 Are you okay?
嗯 圣诞 家人 Yeah. Christmas, family
假期 holidays, you know?
让你觉得伤感吗 It makes you sad?
没有 今年没有 Not really, not this year.
我们感觉就像一家人 We feel like a family.
你会读心啊 You read my mind.
丽兹 Lizzi.
等等 Wait. Hold on.
怎么回事 感觉你们俩密谋什么呢 What- - what is going on? This feels like collusion.
我梦回故乡 ♪Through dreams and just pretending ♪
终于可以在那里 ♪I'm there, and I'll be spending ♪
度过圣诞前夜 ♪Christmas Eve in my hometown ♪
你怎么想 妈妈 What do you say, Mom?
你怎么想 What do you say?
在我的故乡 ♪In my hometown ♪
2012 斯德哥尔摩
-嘿 进来 -你好 Hey, come in. - Hello.
嗨 请进 Hi. Please come in.
看 Look.
贝耶内先生发过来的 Mr. Beyene sent it.
-感觉不错是不是 -是啊 - It's nice, isn't it? - Yeah.
希望我们的工作都会是这个结局 I wish our work always ended like that.
是啊 Yes.
谢谢你跟我分享 Thank you for sharing that with me.
有时候需要提醒一下自己 为什么要 Sometimes it's nice to be reminded why we- -
做出牺牲 Sacrifice.
你也一样 So you, too?
没什么大事 就是女友 孩子 Oh, you know, nothing big- - just girlfriends, children,
也许还会短寿几年 probably a few years off my life.
也许我们可以联手打造 Well, maybe we can build something together
让这一切都变得值得的事业 that will make it all worthwhile.
我想我们可以做到 I think we can.
我们器官移植研究的资金 The funding for our transplant research
就要用完了 is about to run out.
我敢说《柳叶刀》上发表的文章肯定会引起一些关注 I'm sure"The Lancet"article garnered some attention.
是的 我们可以利用这一势头 Yes, we can capitalize on that momentum
获得新的拨款 to secure a new grant,
这样我们就可以做更多的手术 which will lead to more surgeries
也能获得更多的资金 and to more money.
循环往复 Around and around.
直到我们可以扩张到 Until we can expand...
全球 globally.
目标是在未来三个月内进行六次手术 The goal is six operations within the next three months.
你能在这么短的时间里定制出人工气管吗 You can produce that many custom tracheas in that time?
可以 Yes, it can be done.
但我们需要更多的患者 But we need more patients.
那我们就去找更多的患者 Then let's find more patients.